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The Joint FAO–WHO-WOAH Global Early Warning System for health threats and emerging risks at the human–animal–ecosystem interface (GLEWS+)

Advancing one health intelligence to anticipate emerging risks and guide decisions

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One health resources

Learn, Research, Discover

From official reports to interactive datasets, find everything you need to understand and study zoonotic outbreaks worldwide.

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External

The 9th World One Health Congress in Lisbon

The global One Health Community organizes the 9th World One Health Congress in Lisbon 4-7 September 2026

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WHO

WHO Western Pacific: Avian Influenza Weekly Update # 1030: 23 January 2026

From 1 January 2003 to 19 December 2025, a total of 481 cases of human infection with avian influenza A(H5N1) virus have been reported from six countries within the Western Pacific Region.

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WHO

Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2025, 19 December 2025

WHO publishes information on human cases with influenza A(H5N1) avian influenza infection on a monthly basis on the Influenza webpage

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External

ASF report

Test

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FAO, WHO, WOAH

CAVEPM webinar

Canadian Association of Veterinary Epidemiology and Preventive Medicine (CAVEPM) Conference. Calgary - 2025

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WHO

Informe sobre el Grupo de Expertos para la CIPCIZA - Vigilancia, Laboratorio y Evaluación de riesgos intersectorial

Expert group meeting report on surveillance, laboratory work, and risk evaluation.

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WHO

Pre-donning and doffing of PPE by healthcare workers in the event of avian influenza

Steps for safe donning and doffing of PPE for healthcare workers in avian influenza.

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WHO

Recommendations for the early detection of human cases of avian influenza A(H5N1).

Guidance for early detection of human cases of avian influenza A(H5N1).

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WHO

Respiratory sample collection for zoonotic influenza diagnosis (Influenza A/H5 and other zoonotic influenza viruses).

Respiratory sample collection guidance for zoonotic influenza diagnosis.

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WHO

Samples from patients suspected of Influenza A/H5 – Laboratory Testing Algorithm.

Laboratory testing algorithm for suspected influenza A/H5.

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WHO

Epidemiological Update: Avian Influenza A(H5N1) in the Americas Region, 24 January 2025.

Update on H5N1 epidemiology in the Americas as of 24 January 2025.

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WHO

Strengthening the intersectoral work for influenza at the human-animal interface in the Americas Region: technical questions and answers.

Technical Q&A on intersectoral work for influenza surveillance and response.

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WHO

Tripartite Zoonoses Guide (TZG)

Guidance for countries to strengthen coordinated One Health management of zoonotic threats.

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WHO

TZG Operational Tools (OTs)

Practical tools supporting national implementation of the Tripartite Zoonoses Guide.

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WHO

Tripartite MOU

Tripartite technical guidance tools for coordinated One Health action.

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WHO

Joint statements/reports

Shared Tripartite outputs on emerging health threats and coordinated response.

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WHO

RVF DST Tool dashboard

Decision-support tool for assessing Rift Valley fever risk and scenarios.

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WHO

Avian Influenza – Preparing Food Safely (infographic)

Simple guidance on preparing food safely to reduce avian influenza risk.

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WHO

Five Keys for Safer Traditional Food Markets: Risk Mitigation in the Asia-Pacific Region (1)

Regional guidance promoting safer practices in traditional food markets.

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WHO

Five Keys for Safer Traditional Food Markets (video) (1)

Short video on applying the five keys for safer traditional food markets.

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WHO

WHO Rapid Risk Assessments

WHO assessments of emerging threats and their public health risks.

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WHO

WHO Emergency Situation Reports

Country updates on emergencies, response actions, and health impacts.

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WHO

WHO Global Influenza Programme (GIP)

Weekly influenza trends, virology data, and global surveillance.

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WHO

PAHO Epidemiological alerts and updates

PAHO Epidemiological alerts and updates

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WHO

Strengthening global health security at the human-animal interface

Strengthening global health security through One Health collaboration at the human–animal interface.

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WHO

WHO 2019 nCoV-fur-farming risk assessment

WHO assessment of COVID-19 risks linked to fur farming and animal–human transmission.

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WHO

Practical interim guidance to reduce the risk of infection in people exposed to avian influenza viruses

Advice to reduce infection risk among people exposed to avian influenza.

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WHO

Risk assessments and summaries of influenza at the human–animal interface

Monthly assessment of influenza threats at the animal–human interface.

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WHO

Avian influenza A(H7N9) virus

Information on H7N9 virus characteristics, risks, and global epidemiology.

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WHO

Avian influenza A(H5N1) virus

https://www.who.int/teams/global-influenza-programme/avian-influenza/avian-a-h5n1-virus

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WHO

Global Influenza Programme

Latest confirmed outbreaks and key public health updates from WHO.

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WHO, FAO, WOAH

The Quadripartite Joint Offer-A call for targeted investment in One Health

Invitation to fund and strengthen One Health systems worldwide under OH JPA.

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WOAH

WAHIS support desk

Help and guidance for users managing data and reports in WAHIS.

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WOAH

WOAH OH policy briefs

Policy briefs guiding cross-sector One Health actions and strategies.

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WOAH

Wildlife health resources

Resources on wildlife disease, biodiversity & ecosystem health for One Health.

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FAO, WHO, WOAH

ICEID conference poster, 2022

International Conference on Emerging Infectious Diseases (ICEID) Conference. Atlanta - 2022

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FAO, WHO, WOAH

WOHC conference oral presentation, 2024

World One Health Congress (WOHC) Conference. Cape Town - 2024

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FAO, WHO, WOAH

CAVEPM conference poster, 2025

Canadian Association of Veterinary Epidemiology and Preventive Medicine (CAVEPM) Conference. Calgary - 2025

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FAO, WHO, WOAH

Tripartite Commitment 2017

Joint commitment by FAO, OIE, and WHO to strengthen One Health collaboration globally.

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FAO, WHO, WOAH

Tripartite Concept Note 2010

Foundational framework for FAO, OIE, and WHO collaboration on zoonotic disease risks.

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FAO

Rapid risk assessment: foot-and-mouth disease (FMD)

FMD serotype SAT 1 risk assessment

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FAO

ASF situation in Asia & Pacific update

FAO issues regular disease situation updates on a number of key transboundary, epidemic, endemic and emerging diseases.

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FAO

Emerging zoonotic coronaviruses in animals

https://www.fao.org/animal-health/situation-updates/emerging-zoonotic-coronaviruses-in-animals/en

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FAO

Sub-Saharan Africa HPAI

FAO issues regular disease situation updates on a number of key transboundary, epidemic, endemic and emerging diseases.

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FAO

Global AIV with Zoonotic Potential

FAO issues regular disease situation updates on a number of key transboundary, epidemic, endemic and emerging diseases.

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WHO

FAO Risk Monitor platform

Early warning platform providing alerts on food and agriculture risks.

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WHO

FAO’s EMPRES Global Animal Disease Information System (EMPRES-i+)

Global system tracking animal disease events, trends and risk signals.

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WHO

HPAI dashboard

Platform tracking high pathogenicity avian influenza trends and outbreaks.

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WHO

Rapid risk assessments

Joint rapid reviews to support timely evaluation of emerging threats.

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WHO

Updated joint FAO/WHO/WOAH public health assessment of recent influenza A(H5) virus events in animals and people (Assessment based on data as of 1 March 2025)

Public health evaluation of H5 events using data available up to March 2025.

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WHO

Updated joint FAO/WHO/WOAH public health assessment of recent influenza A(H5) virus events in animals and people (Assessment based on data as of 1 July 2025)

Tripartite assessment of recent H5 activity and associated public health risk.

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WHO

Quadripartite One Health Intelligence Scoping Study

Scoping study on One Health intelligence needs across FAO, WHO, WOAH, and UNEP.

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WHO

OH JPA

Foundational agreement defining FAO, WHO and WOAH collaboration.

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FAO, WOAH

Global strategy for the prevention and control of high pathogenicity avian influenza (2024–2033)

FAO–WOAH network providing global expertise on animal influenza viruses.

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WHO

OFFLU

FAO programme supporting early warning, prevention and control of animal diseases.

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WHO

Emergency Prevention System for Animal Health (EMPRES-AH)_WHO Secretariat

Early warning framework to detect and respond to emerging animal health threats.

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WHO

Zoonosis

Overview of zoonoses priorities and activities in the Americas Region.

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WHO

Pan American Center for Foot-and-Mouth Disease and Veterinary Public Health

Information on PANAFTOSA’s work in foot-and-mouth disease and veterinary public health.

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WHO

Rabies

Overview of rabies as a zoonotic disease in the Americas.

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WHO

Report of the Regional Consultation for the Strengthening of Intersectoral Work in the Human-Animal Interface of Influenza.

Report from regional consultation on strengthening intersectoral influenza work.

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WHO

Prevention and Control of Healthcare-Associated Infections.

Guidance on preventing and controlling healthcare-associated infections.

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WHO

Epidemiological Update: Avian Influenza A(H5N1) in the Americas Region, 24 January 2025

Update on H5N1 epidemiology in the Americas as of 24 January 2025.

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WHO

Informe sobre el Grupo de Expertos para la CIPCIZA - Reunión de grupos de trabajo: Vigilancia, Laboratorio y Evaluación de riesgos intersectorial

Expert report on intersectoral surveillance, lab work, and risk assessment.

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WHO

Call to action to establish the Intersectoral Commission for the Prevention and Control of Zoonotic Influenza in the Americas.

Call for establishing an intersectoral commission for zoonotic influenza control.

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WHO

Public health risk assessment associated with the potential occurrence of zoonotic avian influenza A(H5N1) clade 2.3.4.4b in Latin-American and the Caribbean - 6 November 2024

Risk assessment for zoonotic H5N1 clade 2.3.4.4b in Latin America and the Caribbean.

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WHO

Epidemiological alerts and updates. Avian Influenza.

Epidemiological alerts and updates for avian influenza in the Americas.

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WHO

The PAHO/WHO Influenza A(H5N1) Dashboard

Dashboard presenting real-time H5N1 data for the Americas.

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WHO

Timeline – Influenza A(H5N1) Americas Region

Timeline of key events in the H5N1 situation in the Americas Region.

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WHO

Influenza at the Human-Animal Interface: PAHO Recommendations to Strengthen Intersectoral Work for Surveillance, Early Detection, and Investigation, 9 July 2020

Guidance on surveillance and early detection at the human–animal interface.

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WHO

Laboratory diagnostic algorithm for the detection of suspected cases of influenza A/H5

Algorithm for laboratory detection of suspected influenza A/H5 cases.

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WHO

Strengthening the intersectoral work for Influenza at the Human Animal Interface in the Region of the Americas: Technical Questions and Answers

Technical Q&A on intersectoral influenza work at the human–animal interface.

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WHO

Infographic – Respiratory sample collection for zoonotic influenza diagnosis (Influenza A/H5 and other zoonotic influenza viruses)

Respiratory sampling guide for zoonotic influenza diagnosis.

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WHO

Q&A Avian Influenza (Bird Flu)

Q&A resource addressing common questions about avian influenza.

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WHO

Recommendations for the Early Detection of Human Cases of Avian Influenza A(H5N1)

Guidance for early detection of human cases of avian influenza A(H5N1).

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WHO

Infographic – Early Detection of Human Cases of Avian Influenza A(H5N1)

Infographic on detecting early human cases of avian influenza A(H5N1)

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WHO

Infographic – Sample collection for zoonotic influenza diagnosis (Influenza A/H5 and other zoonotic influenza viruses)

Guide to collecting samples for zoonotic influenza A/H5 and related viruses.

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WHO

WHO AFRO Weekly Bulletins on Outbreaks and Other Emergencies

WHO AFRO Weekly Bulletins on Outbreaks and Other Emergencies

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WHO

EpiWin Webinar: Global Public Health Intelligence: WHO Operational Practices (1)

Overview of WHO’s operational practices in health intelligence.

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WHO

WHO COVID-19 Dashboard

Latest global COVID-19 case numbers, trends, and surveillance data.

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WHO

WHO Mpox Dashboard

Global mpox case data, trends, and country reporting.

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WHO

PAHO Public Health Signals and Events - America Region

Signals and events monitored across the Region of the Americas.

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WHO

WHO MERS Dashboard

Current global MERS cases, trends, and surveillance data.

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WHO

WHO EIOS Initiative

Global system supporting early detection of public-health threats.

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WHO

WHO Health Emergency Dashboard

Real-time data on global health emergencies and ongoing crises.

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FAO

EMPRES-i

EMPRES-i + is a web-based application that has been designed by FAO's Emergency Prevention System (EMPRES) to support veterinary services.It provides a centralized system for collecting, organizing, and accessing real-time animal disease data at national, regional, and global levels.

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WHO

Biregional Advocacy Meeting on Risk Mitigation in Traditional Food Markets – Meeting Report

Meeting report on regional strategies for mitigating risks in traditional markets.

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WHO

Traditional Food Markets Can Pose Health Risks (poster)

Poster on risks linked to traditional food markets and how to reduce exposure.

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WHO

Common Symptoms of Influenza (infographic)

Overview of common influenza symptoms for public awareness.

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WHO

Avian Influenza – What You Need to Know (infographic)

Key facts about avian influenza and how to protect yourself and your community.

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WHO

Member States Webstories – Quadripartite Regional Story

Regional coordination story highlighting One Health action across the Western Pacific.

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WHO

Member States Webstories – Indonesia

Indonesia’s One Health surveillance efforts to protect poultry and human health.

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WHO

Member States Webstories – Papua New Guinea

PNG’s multisector collaboration to enhance food safety and prevent public health risks.

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WHO

Member States Webstories – Marshall Islands

Marshall Islands’ progress applying One Health to improve health and environmental safety.

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WHO

Member States Webstories – Kiribati

How Kiribati uses a One Health approach to strengthen food safety and public health.

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WHO

WHO EMRO – One Health

Overview of EMRO’s One Health work, multisector collaboration, and regional priorities.

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WHO

STAR country profile – WHO European Region Risk Atlas (Power BI)

Interactive risk atlas showing country profiles and hazards across the WHO European Region.

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WHO

Preparedness and Resilience for Emerging Threats (PRET)

Framework for strengthening readiness and response to emerging threats.

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WHO

Technical Advisory Group on Virus Evolution (TAG-VE)

Advisory group assessing viral evolution and variant implications.

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WHO

WHO Coronavirus Network (CoViNet)

Global network supporting coronavirus surveillance and lab readiness.

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WHO

Scientific Advisory Group for the Origins of Novel Pathogens

Expert group evaluating scientific evidence on origins of novel pathogens.

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WHO

Strategic and operational plan for coronavirus disease threat management: at a glance

High-level plan for managing coronavirus disease threats and preparedness.

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WHO

WHO global framework to define and guide studies into the origins of emerging and re-emerging pathogens with epidemic and pandemic potential

WHO global framework to define and guide studies into the origins of emerging and re-emerging pathogens with epidemic and pandemic potential

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WHO

SAGO Independent assessment of the origins of SARS-CoV-2

Independent evaluation of the scientific evidence on SARS-CoV-2 origins.

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WHO

COVID-19 (OpenWHO course)

Training course on COVID-19 detection, prevention, and clinical management.

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WHO

SARS-CoV-2 Sero Tracker

Serology-based global mapping of SARS-CoV-2 exposure and immunity.

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WHO

COVID-19 Dashboard

Global dashboard with real-time COVID-19 cases, trends, and surveillance data.

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WHO

Coronavirus disease (COVID-19)

Overview of COVID-19 symptoms, transmission, prevention, and global impact.

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WHO

Risk evaluation of circulating Middle East respiratory syndrome coronavirus (MERS-CoV) clades and lineages

Assessment of circulating MERS-CoV clades and their public-health risk.

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WHO

Research gaps and needs on Middle East respiratory syndrome coronavirus and other emerging zoonotic coronaviruses

Report on MERS-CoV research priorities and evidence gaps.

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WHO

MERSTracker (serotracker)

Serology-based tracking of global MERS-CoV exposure patterns.

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WHO

MERS Dashboard

Real-time global MERS cases, trends, and surveillance data.

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WHO

MERS infographics (1)

Visual materials explaining MERS-CoV facts and prevention.

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WHO

WHO EPI-WIN Webinar: The new WHO MERS-CoV Dashboard

Overview of the new MERS-CoV dashboard and its public-health use.

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WHO

WHO EPI-WIN Webinar: Understanding and implementing WHO’s MERS-CoV investigation protocols

WHO EPI-WIN Webinar: Understanding and implementing WHO’s MERS-CoV investigation protocols

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WHO

WHO EPI-WIN Webinar: MERS-CoV, a circulating coronavirus with epidemic and pandemic potential

Discussion on MERS-CoV risks and One Health preparedness.

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WHO

Middle East respiratory syndrome coronavirus (MERS-CoV)

Overview of MERS-CoV transmission, symptoms, and global situation.

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WHO

Influenza (avian and other zoonotic) health topic page

Overview of avian and zoonotic influenza as a public-health topic.

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WHO

WHO Influenza (avian and other zoonotic) fact sheet

WHO Influenza (avian and other zoonotic) fact sheet

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WHO

Operational guidance on sharing influenza viruses with human pandemic potential (IVPP)

Procedures for sharing influenza viruses with pandemic potential.

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WHO

Case definitions for the four diseases requiring notification to WHO under the IHR (2005)

Case definitions for the four diseases requiring notification to WHO under the IHR (2005)

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WHO

Antigenic and genetic characteristics of zoonotic influenza A viruses and development of candidate vaccine viruses

Case definitions for diseases requiring immediate notification under IHR.

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WHO

Zoonotic Influenza (OpenWHO course)

Training on zoonotic influenza detection, prevention, and response.

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WHO

Manual for the laboratory diagnosis and virological surveillance of influenza (2011)

Manual for diagnosing and performing virological surveillance of influenza.

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WHO

Five keys for safer traditional food markets

Guidance for safer food markets to reduce zoonotic disease transmission.

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WHO

Protocol to investigate non-seasonal influenza and other emerging acute respiratory diseases

Protocol for investigating emerging or unusual influenza outbreaks.

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WHO

Implementing the integrated sentinel surveillance of influenza and other respiratory viruses

Instructions for implementing sentinel surveillance of influenza viruses.

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WHO

Surveillance for human infections with avian influenza A(H5) viruses

Guidance for detecting human infections with avian influenza A(H5).

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WHO

Influenza surveillance outputs

Latest laboratory and surveillance data on influenza activity worldwide.

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WHO

Zoonotic influenza infographic

Visual overview explaining zoonotic influenza risks and transmission.

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WHO

Respiratory Investigations and Studies (Unity Studies)

Respiratory pathogen study platform supporting global surveillance.

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WHO

WHO GISRS Unity Studies

WHO-supported global studies investigating influenza transmission.

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WOAH

Tool for Influenza Pandemic Risk Assessment (TIPRA)

Framework for assessing global influenza pandemic risk.

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WOAH

Influenza (avian and other zoonotic) Outbreak Toolbox

Toolkit for responding to avian and zoonotic influenza outbreaks.

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WHO

Episode #118 – Avian Influenza (13 May 2024)

Short expert briefing explaining current avian influenza risks.

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WHO

WHO EPI-WIN Webinar: Public health risk of avian influenza A(H5N1) detected recently in dairy cattle (6 May 2024) (1)

WHO EPI-WIN Webinar: Public health risk of avian influenza A(H5N1) detected recently in dairy cattle (6 May 2024)

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WHO

WHO EPI-WIN Webinar: Avian influenza H5 – an update (6 June 2024)

WHO EPI-WIN Webinar: Avian influenza H5 – an update (6 June 2024)

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WHO

WHO Disease Outbreak News (DON)

Latest confirmed outbreaks and key public health updates from WHO.

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FAO

FAO One Health webpage article Highlighting GLEWS+.

The Tripartite Global Early Warning System (GLEWS+) serves as an indispensable tool, facilitating the identification of shifts in disease patterns and enhancing our ability to proactively detect and respond to potential threats to both animal and human health.

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WOAH

Joint public health risk assessment Avian influenza

Tripartite assessment of current H5 avian influenza risks to animals and humans.

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WOAH

WAHIS

Global animal-disease reporting system with official data reported by WOAH Members.

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WOAH

Global Situation page of the wildlife health portal

Worldwide data on antimicrobial use in animals — supports AMR surveillance.

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WOAH

WOAH - Substandard and Falsified Veterinary Products (1)

WOAH addresses the circulation of substandard and falsified veterinary products (SFVPs) through its SFVP programme. The more Members participate in its surveillance initiatives, the stronger the global response to SFVPs – ensuring only safe, effective veterinary medicines reach the market.

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WOAH

WOAH - One health page

WOAH - One health page

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WHO

Infographic – From Sample to Influenza Vaccine

Infographic showing how influenza samples lead to vaccine development.

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WHO

Experiences and Recommendations in the Clinical Management of Avian Influenza A(H5N1) (1)

Clinical insights and recommendations for managing human H5N1 infections.

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FAO, WHO, WOAH

GLEWS+ brochure

Overview of GLEWS+ and how FAO, WHO, and WOAH collaborate on early warning of health threats.

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FAO, WOAH

Avian Influenza Matching Project (AIM)

Project under OFFLU/WOAH focusing on global avian-influenza surveillance and data sharing.

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FAO, WHO, WOAH

Quadripartite One Health Joint Plan of Action (OHJPA)

2022–2026 joint roadmap to prevent and respond to health risks across humans, animals, plants, environment.

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FAO, WOAH

Vaccine Composition Meeting (VCM) six-month report

This document defines the roles of OFFLU (WOAH and FAO network of expertise on animal influenza) to the WHO influenza vaccine virus selection process. The proposed duration is up to 5 years (1 January 2024 – 31 December 2028)

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FAO, WOAH

OFFLU webpage

OFFLU is a network of expertise on animal influenza established jointly in 2005 by the World Organisation for Animal Health (WOAH) and the Food and Agriculture Organization of the United Nations (FAO) to support and coordinate global efforts to prevent, detect and control influenzas in animals.

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WHO

WHO EPIWIN: One Health Intelligence: Global Collaboration for Emerging Health Threat Detection

How GLEWS+ strengthens joint early warning through Tripartite One Health intelligence.

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FAO

Framework for early warning of animal health threats

This framework lays out the technical objectives and the structural and institutional set-up for the operationalisation and management of Early Warning Systems against infectious animal diseases.

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WHO

Pre-donning and doffing of PPE by farm workers exposed to avian influenza

Steps for safe donning and doffing of PPE for farm workers exposed to avian influenza.

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WOAH, WHO, FAO

OH Joint Plan of Action (OHJPA) Fact Sheet

Concise summary of OH JPA’s priorities and planned collaborative One Health actions.

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FAO, WHO, WOAH

A guide to implementing the One Health Joint Plan of action at national level.

Practical guidance from countries to adopt the joint plan of Action framework domestically.

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WHO

Dunja test

DON

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WHO, FAO, WOAH

test publication 1

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WHO

Five Keys for Safer Traditional Food Markets (video)

Short video on applying the five keys for safer traditional food markets.

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WHO

Five Keys for Safer Traditional Food Markets: Risk Mitigation in the Asia-Pacific Region

Regional guidance promoting safer practices in traditional food markets.

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