From 1 January 2003 to 19 December 2025, a total of 481 cases of human infection with avian influenza A(H5N1) virus have been reported from six countries within the Western Pacific Region.

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Update on H5N1 epidemiology in the Americas as of 24 January 2025.

Guidance for countries to strengthen coordinated One Health management of zoonotic threats.

Practical tools supporting national implementation of the Tripartite Zoonoses Guide.

Tripartite technical guidance tools for coordinated One Health action.

Simple guidance on preparing food safely to reduce avian influenza risk.

Regional guidance promoting safer practices in traditional food markets.

Short video on applying the five keys for safer traditional food markets.

Strengthening global health security through One Health collaboration at the human–animal interface.

Information on H7N9 virus characteristics, risks, and global epidemiology.

https://www.who.int/teams/global-influenza-programme/avian-influenza/avian-a-h5n1-virus

Latest confirmed outbreaks and key public health updates from WHO.

Invitation to fund and strengthen One Health systems worldwide under OH JPA.

Policy briefs guiding cross-sector One Health actions and strategies.

Foundational agreement defining FAO, WHO and WOAH collaboration.

FAO–WOAH network providing global expertise on animal influenza viruses.

FAO programme supporting early warning, prevention and control of animal diseases.

Early warning framework to detect and respond to emerging animal health threats.

Overview of zoonoses priorities and activities in the Americas Region.

Information on PANAFTOSA’s work in foot-and-mouth disease and veterinary public health.

Overview of rabies as a zoonotic disease in the Americas.

Update on H5N1 epidemiology in the Americas as of 24 January 2025.

Call for establishing an intersectoral commission for zoonotic influenza control.

Epidemiological alerts and updates for avian influenza in the Americas.

Timeline of key events in the H5N1 situation in the Americas Region.

Q&A resource addressing common questions about avian influenza.

Infographic on detecting early human cases of avian influenza A(H5N1)

Guide to collecting samples for zoonotic influenza A/H5 and related viruses.

Global mpox case data, trends, and country reporting.

Global system supporting early detection of public-health threats.

Poster on risks linked to traditional food markets and how to reduce exposure.

Overview of common influenza symptoms for public awareness.

Key facts about avian influenza and how to protect yourself and your community.

Regional coordination story highlighting One Health action across the Western Pacific.

Indonesia’s One Health surveillance efforts to protect poultry and human health.

PNG’s multisector collaboration to enhance food safety and prevent public health risks.

Marshall Islands’ progress applying One Health to improve health and environmental safety.

How Kiribati uses a One Health approach to strengthen food safety and public health.

Overview of EMRO’s One Health work, multisector collaboration, and regional priorities.

Interactive risk atlas showing country profiles and hazards across the WHO European Region.

Framework for strengthening readiness and response to emerging threats.

Advisory group assessing viral evolution and variant implications.

Global network supporting coronavirus surveillance and lab readiness.

Expert group evaluating scientific evidence on origins of novel pathogens.

Overview of COVID-19 symptoms, transmission, prevention, and global impact.

Visual materials explaining MERS-CoV facts and prevention.

Overview of MERS-CoV transmission, symptoms, and global situation.

Visual overview explaining zoonotic influenza risks and transmission.

Short expert briefing explaining current avian influenza risks.

The Tripartite Global Early Warning System (GLEWS+) serves as an indispensable tool, facilitating the identification of shifts in disease patterns and enhancing our ability to proactively detect and respond to potential threats to both animal and human health.

Infographic showing how influenza samples lead to vaccine development.

Overview of GLEWS+ and how FAO, WHO, and WOAH collaborate on early warning of health threats.

2022–2026 joint roadmap to prevent and respond to health risks across humans, animals, plants, environment.

Concise summary of OH JPA’s priorities and planned collaborative One Health actions.

Short video on applying the five keys for safer traditional food markets.

From 1 January 2003 to 19 December 2025, a total of 481 cases of human infection with avian influenza A(H5N1) virus have been reported from six countries within the Western Pacific Region.

WHO publishes information on human cases with influenza A(H5N1) avian influenza infection on a monthly basis on the Influenza webpage

Expert group meeting report on surveillance, laboratory work, and risk evaluation.

Shared Tripartite outputs on emerging health threats and coordinated response.

WHO assessments of emerging threats and their public health risks.

Country updates on emergencies, response actions, and health impacts.

PAHO Epidemiological alerts and updates

WHO assessment of COVID-19 risks linked to fur farming and animal–human transmission.

Monthly assessment of influenza threats at the animal–human interface.

Resources on wildlife disease, biodiversity & ecosystem health for One Health.

Joint commitment by FAO, OIE, and WHO to strengthen One Health collaboration globally.

Foundational framework for FAO, OIE, and WHO collaboration on zoonotic disease risks.

FMD serotype SAT 1 risk assessment

FAO issues regular disease situation updates on a number of key transboundary, epidemic, endemic and emerging diseases.

https://www.fao.org/animal-health/situation-updates/emerging-zoonotic-coronaviruses-in-animals/en

FAO issues regular disease situation updates on a number of key transboundary, epidemic, endemic and emerging diseases.

FAO issues regular disease situation updates on a number of key transboundary, epidemic, endemic and emerging diseases.

Joint rapid reviews to support timely evaluation of emerging threats.

Public health evaluation of H5 events using data available up to March 2025.

Tripartite assessment of recent H5 activity and associated public health risk.

Scoping study on One Health intelligence needs across FAO, WHO, WOAH, and UNEP.

Report from regional consultation on strengthening intersectoral influenza work.

Expert report on intersectoral surveillance, lab work, and risk assessment.

Risk assessment for zoonotic H5N1 clade 2.3.4.4b in Latin America and the Caribbean.

WHO AFRO Weekly Bulletins on Outbreaks and Other Emergencies

Meeting report on regional strategies for mitigating risks in traditional markets.

High-level plan for managing coronavirus disease threats and preparedness.

WHO global framework to define and guide studies into the origins of emerging and re-emerging pathogens with epidemic and pandemic potential

Independent evaluation of the scientific evidence on SARS-CoV-2 origins.

Assessment of circulating MERS-CoV clades and their public-health risk.

Report on MERS-CoV research priorities and evidence gaps.

Latest laboratory and surveillance data on influenza activity worldwide.

Latest confirmed outbreaks and key public health updates from WHO.

Tripartite assessment of current H5 avian influenza risks to animals and humans.

Worldwide data on antimicrobial use in animals — supports AMR surveillance.

WOAH addresses the circulation of substandard and falsified veterinary products (SFVPs) through its SFVP programme. The more Members participate in its surveillance initiatives, the stronger the global response to SFVPs – ensuring only safe, effective veterinary medicines reach the market.

Project under OFFLU/WOAH focusing on global avian-influenza surveillance and data sharing.

This document defines the roles of OFFLU (WOAH and FAO network of expertise on animal influenza) to the WHO influenza vaccine virus selection process. The proposed duration is up to 5 years (1 January 2024 – 31 December 2028)

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Steps for safe donning and doffing of PPE for healthcare workers in avian influenza.

Guidance for early detection of human cases of avian influenza A(H5N1).

Respiratory sample collection guidance for zoonotic influenza diagnosis.

Laboratory testing algorithm for suspected influenza A/H5.

Technical Q&A on intersectoral work for influenza surveillance and response.

Advice to reduce infection risk among people exposed to avian influenza.

Guidance on preventing and controlling healthcare-associated infections.

Guidance on surveillance and early detection at the human–animal interface.

Algorithm for laboratory detection of suspected influenza A/H5 cases.

Technical Q&A on intersectoral influenza work at the human–animal interface.

Respiratory sampling guide for zoonotic influenza diagnosis.

Guidance for early detection of human cases of avian influenza A(H5N1).

WHO Influenza (avian and other zoonotic) fact sheet

Procedures for sharing influenza viruses with pandemic potential.

Case definitions for the four diseases requiring notification to WHO under the IHR (2005)

Case definitions for diseases requiring immediate notification under IHR.

Manual for diagnosing and performing virological surveillance of influenza.

Guidance for safer food markets to reduce zoonotic disease transmission.

Protocol for investigating emerging or unusual influenza outbreaks.

Instructions for implementing sentinel surveillance of influenza viruses.

Guidance for detecting human infections with avian influenza A(H5).

Clinical insights and recommendations for managing human H5N1 infections.

OFFLU is a network of expertise on animal influenza established jointly in 2005 by the World Organisation for Animal Health (WOAH) and the Food and Agriculture Organization of the United Nations (FAO) to support and coordinate global efforts to prevent, detect and control influenzas in animals.

This framework lays out the technical objectives and the structural and institutional set-up for the operationalisation and management of Early Warning Systems against infectious animal diseases.

Steps for safe donning and doffing of PPE for farm workers exposed to avian influenza.

Practical guidance from countries to adopt the joint plan of Action framework domestically.

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Regional guidance promoting safer practices in traditional food markets.

Decision-support tool for assessing Rift Valley fever risk and scenarios.

Weekly influenza trends, virology data, and global surveillance.

Help and guidance for users managing data and reports in WAHIS.

Early warning platform providing alerts on food and agriculture risks.

Global system tracking animal disease events, trends and risk signals.

Platform tracking high pathogenicity avian influenza trends and outbreaks.

Dashboard presenting real-time H5N1 data for the Americas.

Latest global COVID-19 case numbers, trends, and surveillance data.

Signals and events monitored across the Region of the Americas.

Current global MERS cases, trends, and surveillance data.

Real-time data on global health emergencies and ongoing crises.

EMPRES-i + is a web-based application that has been designed by FAO's Emergency Prevention System (EMPRES) to support veterinary services.It provides a centralized system for collecting, organizing, and accessing real-time animal disease data at national, regional, and global levels.

Training course on COVID-19 detection, prevention, and clinical management.

Serology-based global mapping of SARS-CoV-2 exposure and immunity.

Global dashboard with real-time COVID-19 cases, trends, and surveillance data.

Serology-based tracking of global MERS-CoV exposure patterns.

Real-time global MERS cases, trends, and surveillance data.

Training on zoonotic influenza detection, prevention, and response.

Respiratory pathogen study platform supporting global surveillance.

WHO-supported global studies investigating influenza transmission.

Framework for assessing global influenza pandemic risk.

Toolkit for responding to avian and zoonotic influenza outbreaks.

Global animal-disease reporting system with official data reported by WOAH Members.

WOAH - One health page